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Non-invasive glucose monitoring, inkjet technologies, and serendipity in Open Innovation (Nov 20 2014)
Sterilizing vials, manufacturing oxalic acid, and introductions (Oct 01 2014)
Sterilizing vials, manufacturing oxalic acid, and introductions (Jun 23 2014)
Battery monitoring, substrate polishing, and sources of growth (May 14 2014)
Sterility, Dispersions, and one more question (Apr 03 2014)
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 yet2.com Technology Marketplace Report for Feb 15 2012
 featuring: Health, Wellness, Personal Care & Analysis
 Featured TechPaks  Featured TechNeeds
 Technology solutions provided by companies  Technology needs sought after by companies
Portfolio of technologies for the fast and accurate detection and identification of pathogens, environmental contaminants, and illicit materials
The University of Georgia Research Foundation, Inc. is seeking to license its portfolio of technologies for the fast and accurate detection and identification of pathogens and chemicals. The technologies provide for a scalable and inexpensive method for the detection of disease agents as well as environmental contaminants, materials of relevance to homeland security, etc. Applications include food and pharmaceutical industries, medical and veterinary fields, transportation security, research labs, environmental control, among others. This is a portfolio comprising several uses of a nanotechnology-based platform technology for the fast and accurate detection and identification of biologic or chemical analytes present in ultra-low concentrations. Using SERS (Surface Enhanced Raman Spectroscopy) detection of analytes can be carried out even at concentrations below 0.1 microMolar down to about 0.01 picoMolar. Analytes succesfully tested include food contaminants (e.g., melamine), chemicals, pathogens (viruses, bacteria, mold, mycoplasma, etc.). The technology is suitable for use in connection with liquids and gaseous solutions and mixtures.

Prest-VEGF promotes chronic wound healing even against aggressive proteinase attack
Protease-resistant VEGF (prest-VEGF) is the modification of a growth factor that is essential for wound healing, and can be used therapeutically for hard-to-heal chronic wounds such as diabetic ulcers. Endogenous growth factors, such as VEGF, EGF, FGF, IGF, TGF beta1, and PDGF are essential for wound healing. Even chronic wounds still produce these growth factors, but serine proteinases such as plasmin degrade them so that there is a deficiency at the wound site. Previous attempts to deploy growth factors in treating chronic wounds have failed clinically, primarily because of the instability of the protein, the highly aggressive proteinases found in the wound environment, and the rapid clearance or wash-out of the protein. Bayer Prest-VEGF has stabilized the cleavage site of VEGF by genetically engineered amino acid exchange. This protects the mutant protein (VEGF) against proteinase attack, thus making it resistant to proteinase. Protease-resistant VEGF thus becomes available to the body's healing mechanisms.

Bio-compatible bone plug
A medical research institute has developed a bio-compatible bone plug for hip prostheses. Sooner or later prostheses loosen up. During the loosening, the bone weakens; as a result the risk of the surgery exponentially increases. There are two kind of hip prostheses: cement-restricted hip prostheses and cement-free hip prostheses. Our partner developed a bio-compatible bone plug for cement-restricted hip prosthesis. Bio-compatible bone plugs keep the cement (which holds the hip prosthesis) from getting into the bone cavity, and totally fills up the gaps between the bone and the prosthesis, because this ensures the proper fastening of the prosthesis. After it has fulfilled its function, it is absorbed by the body fluids. Tests were performed in order to determine the mechanical, physiological, viscoelastical, temperature related stability and the solubility of the material. The mechanical stability was determined with a press. The solubility of the substance was also tested in vitro. Animal tests were preformed on pot-bellied pigs.

A liquid anode radiation source with head stand capability
THis liquid anode radiation source offers head stand capability. Our client is looking for partners to further improve the new type of patented x-ray tubes, to develop it into a product, and to launch it on the market. In the area of x-ray tubes, the trend in technical development is currently toward reducing the size of the focal spot, raising the thermal loadability of the anode, and raising the maximum current. A significant increase in the maximum tube current has been made possible through the introduction of the rotating anode, the use of which reduces the heat load on the anode by distributing the heat over a larger surface. The next technical improvement in terms of loadability was the introduction of the liquid anode, but the issue of stabilizing the flow of fluid has not been resolved. It only operates in a particular orientation or the electron cloud used in creating the x-radiation must be transmitted through a thin window, which is highly vulnerable. The current technology represents a general source of x-radiation capable of resolving or surmounting these problems. Very large tube currents can be attained in the array while the size of the focal spot is reduced. The array that constitutes the invention facilitates operation in any orientation, and with it the electron window can be abandoned. In certain cases, the technology is capable of operating at several times a constant tube power of 5kW.

BODY-ALINE: The world's first back-strengthening and posture correction exercise machine
Medical experts agree that poor posture is the root cause of most back pain, however, there has yet to be any easy solution for permanently correcting posture... until now. The BODY-ALINE is the first exercise machine specifically designed to strengthen the back and realign the spine in one easy motion to improve appearance and relieve chronic back pain. Made for the home, office or gym, it requires just 1-2 minutes a day without a change of clothes or ounce of sweat. Simply sit down, lean back and rotate your arms. The targeted exercise motion strengthens the back, massages the spine and retrains postural muscles to go in the exact opposite direction of a slouch -- this is called "Mirror Image Muscle rfehabilitation." Most people stand taller and feel the benefit of the machine after the very first use. This product replaces the cumbersome, complicated and laborious rehabilitative floor exercises (McKenzie Program) that most doctors give their patients for back pain. In addition to the medical field, it's purchased by at-home customers, some from as far away as Australia, UK, Ireland, South Korea, Ireland, Scotland, Greece, Singapore, India and the Philippines -- with no direct advertising to these countries. International customers pay a premium for shipping that often times exceeds the cost of the machine! With global exposure, sales of this product could grow exponentially.

Low-cost and robust indoor positioning system utilizing a conventional wireless LAN network
Indoor positioning system utilizing a wireless sensor network has been developed and mobile phones are applied to the terminals. This indoor wireless positioning system has high robustness to signal loss, noise, and signal fluctuation due to multipath interference. Emergency signal transfer system were demonstrated at commercial buildings that can alert and guide users to the nearest emergency exit by means of mobile phones. Applications include positioning users, robot movement support, determining conditions of indoor environments and detecting emergencies. AIST has developed a robust positioning system utilizing ZigBeeTM (a wireless sensor network on the 2.4 GHz ISM band) that is robust to signal loss, noise, and signal fluctuation due to multipath interference. The developed positioning system applies stochastic reasoning in analyzing the ID and RSSI (received signal strength indication) of received wireless signals. The position of people or target objects can be estimated within a margin of error of from one to several meters regardless of signal loss, noise, or signal fluctuation due to multipath interference. The developed software implementing stochastic reasoning analyzes IEEE 802.15.4 packets that underlie ZigBeeTM communication protocol. It is significantly less computationally intensive and can even run on mobile phones. The system has been installed and tested at Landmark Plaza in Yokohama City, Japan and its functionality in a real environment is verified.

Seeking: Naturally derived chemicals that exhibit pesticidal effects
Many natural organisms produce substances with pesticidal effects or substances that can be concentrated from natural sources for enhanced effect. We are seeking the chemistries behind these effective natural substances that have efficacies comparable to commercial pest control standards. We are seeking biorational approaches to new pesticides. "Biorational" approaches include processes, organisms, or chemistries that occur spontaneously in nature. A biorational pesticide is defined as "A chemical such as a toxin or growth regulator derived from a living organism and applied either as the entire dead organism or as an extract from the organism." For example, a tree may generate allelopathic substances or antibiotics to protect itself from predation by insects, fungal pathogens, or to prevent colonization by other plant species nearby. Currently, we are not seeking approaches that include genetic engineering or synthetic derivatives of natural products.

Seeking: Effective and efficient care and freshness actives deposition aid
Improved fabric feel, softness, long lasting freshness, color rejuvenation, wrinkle reduction, and soil release benefits are the top unmet consumer needs. Care and freshness actives that drive these benefits need to be delivered to the fabric either through the wash or rinse-added products. The challenge of delivery of care and sensoriality actives onto substrates such as fabric through-the-wash involves two seemingly contradictory processes. The cleaning agents (surfactants) treat care and sensoriality actives as soil -- emulsifying, solublizing, and removing them from the wash systems. Deposition of benefit agents in the presence of cleaning agents is often exceedingly difficult without the use of deposition aid systems. Some deposition aid technology can be efficient, but additional challenges are that most are not selective. The deposition aid can also bring soils with active agents to the fabric resulting in negative cleaning performance. Hence, a deposition aid that is selective and efficient is needed. We are seeking to partner with external experts to identify novel technologies that can effectively and efficiently deposit care and freshness actives onto fabrics (silicones, perfume micro capsules) without cleaning negatives, preventing machine and fabric buildup.

Seeking: Technologies that improve the state of the art of recycling
Recycling is fast becoming an integral part of our everyday life, yet there has been very little innovation in the area to make the act simpler, easier, fun, and less odorous. We are looking for a product or technology that would: 1. Make the process of in-home recycling easier and more streamlined. 2. Contain or eliminate the odors and insects that are associated with storing used food and drink containers. 3. Any technology or product that would be regarded as a game changer in the recycling arena. We would like to find a range of methods or technologies filling this need. The company is open to licensing arrangements.

Seeking: Technologies that eliminate household odors within closed containers
Trash odors are among the worst in the house. Trash cans and waste baskets do not adequately control the odor, and the can material itself might retain malodors. A technology that can be incorporated with a container/trash can that will eliminate odors while storing trash; keeping the container and the room odor free. We have tried a device containing activated carbon that attaches to the lid and absorbs the odor in the air space. This was not satisfactory.

Seeking: Long-lasting freshness in hard-surface cleaning
Existing hard-surface cleaners usually rely on conventional perfume technology to deliver scent onto surfaces being cleaned and to release it into the environment. Even when they are formulated to be highly persistent, conventional perfumes rarely achieve an effect that lasts longer than a couple of hours. We think consumers would be highly appreciative of hard-surface cleaning products able to offer breakthrough perfume longevity benefits, e.g. lasting at least half a day. We are interested in any type of perfume release technology that may deliver a significant and consumer-noticeable long-lasting freshness effect in a hard-surface cleaning context, especially in floor cleaning. It is critical that the perfume release technology does not introduce cleaning or shine deficiencies which may negatively affect the consumer acceptance of a hard-surface cleaner. It is equally important that the technology has an affordable cost and/or is highly weight efficient, due to the low consumer price of these products, which results in relatively low formula cost affordability.

Seeking: Professional oral care diagnostics with high consumer conversion
Seeking to provide an inventory of professional diagnostics that have high consumer conversion potential. They don't need to be able to diagnose disease, but rather just need to provide guidance to consumers, and identify those that are at-risk. This should include; technology, business models, and trends. Emphasis to be placed on: a) tooth integrity (early signs of decay, demineralization, caries, erosion); b) gum health (inflammation, perio, recession)

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