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Sterilizing vials, manufacturing oxalic acid, and introductions (Jun 23 2014)
Battery monitoring, substrate polishing, and sources of growth (May 14 2014)
Sterility, Dispersions, and one more question (Apr 03 2014)
Motor-winding, dielectric fluids for transformers, and an invisibility cloak (Mar 13 2014)
Heart therapies, solar collector, and OI portals for your company (Feb 20 2014)
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 yet2.com Technology Marketplace Report for Jan 11 2012
 featuring: Packaging & Medical
 Featured TechPaks  Featured TechNeeds
 Technology solutions provided by companies  Technology needs sought after by companies
Innovative nozzle produces ultrafine droplets and consistent spray patterns even at low pressures for unprecedented operating cost savings
Energy-saving nozzles for spray systems save on operational and capital equipment costs by using lower pressures and less piping while achieving finer mists and better coverage. The nozzles are appropriate for liquids, colloids, gases, and some slurries (depending on particle size). Parker-Hannifin Macrospray(R) technology nozzles offer droplet sizes down to 25 microns at operating pressures as low as 100 psi. An inlet pressure of 1000psi results in a droplet size typically less than 10 microns. Because the Macrospray technology does not rely on compressed air, Parker nozzles also atomize better and more efficiently at lower pressures than do other nozzles. The technology is fully commercialized. Parker-Hannifin Macrospray(R) nozzles are backed by years of testing and validation. They result in significantly longer life and higher process operating efficiencies. The Parker nozzles are produced from digital tools with the flow features chemically etched in substrates that are diffusion welded resulting in a monolithic structure. This robust manufacturing process leads to reproducible internal and external features and life-long, consistent spray patterns. Hydraulically smooth internal surfaces reduce flow losses and maximize efficiency. Nozzle passages, including metering slots, spin chambers, and exit orifices are designed to minimize pressure drop to conserve pump energy.

Efficient device for eliminating smoke particles in residential and commercial construction for fire protection
The invention uses high-frequency circuits and fly-back transformers to generate a high voltage electric field, and eventually an electric arc in the air. This arc plasma consists of energetic electrons and ions. When an energetic electron impinges upon a smoke particle, the latter is ionized into an electron and a positively charged heavy ion, which in turn is attracted and attached to the negative electrode, leading to the zapping of such a smoke particle. The invented device can be deployed in residential and commercial buildings for fire protection. Additionally, it can be made into portable form such that it can be unplugged from persistent charging state and carried to wherever it is needed. Prototype is developed. Proved technical concept with mock-up samples available. More advanced powerful versions are currently in development. The organization is interested in finding license partners.

Highly customizable ionic liquids with components made from renewable resources
DuPont's technology produces a "tunable" ionic liquid that exhibits negligible vapor pressure, simplifying conformance with environmental regulations and allowing ease of solvent recycling. By selecting cations and anions appropriate to the reaction, reaction products can be drawn off as a separate phase and the solvent can be reused. The DuPont technology comprises ionic liquids containing heterocyclic cations and fluorinated, sulfonated anions useful as solvents for a broad class of reactions including aromatic electrophilic substitution, polymerization, etherification, nitration, acylation, esterification, oligomerization, transesterification, isomerization and hydration. Cations may be made using DuPont bio-PDO-based source materials from renewable sources.

Proteinase-inhibitor ACT restarts healing in chronic wounds, reduces inflammation
Alpha-1-Antichymotrypsin (alpha1 ACT) is a proteinase-inhibitor for improvement of wound healing. ACT is a substance deficient in chronic wounds. Normally, it blocks Cathepsin G, a protein that breaks down tissues. Supplying ACT as a therapeutic significantly helps chronic wounds to heal. A lab-scale and semi-technical fermentation process for human recombinant ACT has been developed, and broad patent protection has been obtained. Many diabetics and long-term care patients can experience chronic wounds where normal tissue healing is disrupted. Such wounds can be caused by everyday friction of apparel or bedclothes; they can result in infection, amputation, and death. In tests using transgenic diabetic mice, improved, dose-dependent wound closure occurred with ACT. In acute wounds, levels of alpha1-ACT are sufficient to suppress pathologic levels of proteinases that inhibit wound healing. In chronic wounds, however, the supply of alpha1-ACT is not sufficient to block the proteinases. This deficiency leads to an increase in matrixmetalloproteinases such as MMP-9 (a promoter of inflammation), Cathepsin G, and others such as Chymotrypsin and Plasmin. Thus, alpha1-ACT restores the impaired natural proteinase inhibitor shield and restarts wound healing. In a transgenic diabetic mouse model, the quality of newly formed wound tissue is improved (monitored as an increase in tensile strength). Wound closure time is significantly reduced (dose-related) with topical application of ACT, and natural tissue structure (e.g. collagen structure) is completely restored.

Method and diagnostic kit for diagnosing susceptibility of post-traumatic scar tissue formation
Our partner, a Hungarian university, has developed a new method for diagnosing susceptibility of post-traumatic scar tissue formation. The client is interested in finding producers and/or a product developer to acquire the patent rights through an in-license agreement and also interested in potential distributors. Background information: Benign airway stenosis (BAS) is currently considered to be a multifactorial disorder in which, primarily, an injury to the tracheal mucosa and, additionally, the circumstances of intubation, general condition of the patient, microcirculation of the affected tracheal tissue layers, etc., serve as the key features in the pathogenesis of the disease. The Challenge: The invention is a PCR-based method and a diagnostic kit for diagnosing post-traumatic scar tissue formulation with the TGF-beta1 gene-specific sequence. If the patient carries this gene's homozygotic wild type allele, then this patient is considered to be susceptible to post-traumatic scar tissue. Innovation: The present invention is based on the surprising and unexpected finding that the ratio of the C/C genotype of -509 C/T TGF-beta1 polymorphisms is higher among patients with post-traumatic tracheal scar tissue. Therefore, the determination of this polymorphism offers a good possibility to forecast susceptibility to the development of post-traumatic tracheal scar tissue. The research phase has been successfully closed, while the patenting process is in progress. The next step will be to enter the product development phase.

Seeking: Technologies that remove air and moisture from within closed containers
Many types of food spoilage are slowed when air and moisture are removed from around the food, however currently available solutions are expensive, take up too much space, and require an involved process. This organization is seeking a technology that can be incorporated with a container that will remove air and moisture with the single push of a button. Previously, they've tried a countertop appliance that pulls a vacuum on a bag and seals it with heat, but this was expensive and too large a solution.

Seeking: Technical approaches to improve indoor air quality for homes, especially in highly polluted cities
The source of indoor air pollution is not same for all consumers in urban developing markets. The primary pollutant sources for the upper and middle class in many of these countries is automobile emissions, fossil-fuel burning for industry, and dust related to arid climates. These consumers live in houses or apartments in densely populated urban cities and for the most part have running water and electricity most of the time, but not always. Consumers at lower economic classes experience additional pollutants due to burning coal, animal waste, oil, or wood for cooking indoors. For these consumers the availability of electricity and running water is rare. Based on our corporate purpose and commitment to improving the lives of more consumers in more parts of the world, we seek to understand how to decrease the frequency and severity of respiratory illness in homes with adults, teens and children (children age 0 to 5 years of age). The need is especially apparent given the mortality rates of children with such illnesses in developing regions. Much of the research in this area has named air pollution as the cause. Procter and Gamble would like to provide affordable indoor air quality improvement solutions to consumers via an Air Purification device. We would like to identify a third party air purifier partner who can: o Provide us a currently commercialized/available air purifier. o Could assist with future development and innovation in this category. Please see the TechNeed for a list of previously attempted solutions, requirements for a successful solution, and comments.

Seeking: Technologies to increase the activity of fungicides by mitigating mechanisms of fungicide resistance
Fungicides are used widely to control a broad range of fungal pathogens that infect crop plants. This organization seeks new substances and approaches that enhance fungicidal activity by improving the degree of preventive or curative control, and the spectrum of control, through mitigating fungal resistance mechanisms. There appears to be two methods by which to overcome resistance: One, overcome resistance directly with a substance or approach that is stronger than the target species resistance factor. Two, through interruption or mitigation of the mechanism of resistance in the target species. Known approaches include the use of synergists which lowers target species resistance factor via interaction with fungicide chemistry receptor sites, inducers of systemic acquired resistance (SAR) which trigger defense mechanisms within the host species, combinations of multiple modes-of-action, or other methods of mitigating conjugation or metabolism of fungicides within the target species. This organization would like to discover a cost-effective substance or approach that mitigates the problem of fungi developing resistance to applied fungicides. Your solution would result in an improvement in commercial fungicidal activity (lower dose rates, increased disease spectrum, improved control consistency, and so forth) versus current commercial standards. As part of your proposed solution, you should include a description of your capabilities and the type of business arrangement you seek, and suggest ideas about how to validate and assess the technology.

Seeking: Improved ink appearance and adhesion to polyolefin films and fibers
We are seeking means to improve aqueous ink appearance and adhesion to polyolefin films and fibers. This is intended to reduce ink usage while improving graphic appearance and wear during packaging, product transport, and usage. Methods of improvement can be in the form of additives to the inks or pretreatment of the substrate by electrical, mechanical, or chemical means. The desired variable cost of the technology is to be less than $0.01 per 1000 sq meters. We are not looking for cross-linking systems like IR, UV or E-Beam; flame plasma treatments for these applications; technology that has not yet been commercialized; or additives to the polyolefin film and fiber resins. This is a global need and applies to low basis weight packaging and product polyolefin films and fibers. The chemistry or system is to be non-hazardous and generally recognized as safe. The technology should improve the drying rate of the ink, not increase drying time. We would prefer that our partner have global IP in these technology areas.

Seeking: Improvements in rainwater collection and use
Rainwater collection is a necessity in some parts of the world and a nutrient-rich watering solution for gardeners everywhere. We are looking for a product or technology that would: 1. Decoratively hide the rainwater collector while simplifying water dispensing. 2. Find novel collection embodiments that facilitate water dispensing without the use of pumps. 3. Eliminate or control the propagation of insects and bacteria at the collection site. 4. Alternative methods for delivering the collected water to the place of use. We would like to find a range of methods or technologies filling this need. The company is open to licensing arrangements.

Seeking: Long-lasting perfume delivery
We are looking for a sustained/slow/triggered perfume release technologies or innovations capable of delivering breakthrough long-lasting perfume performance (i.e., 24 hours after product application) in today's beauty care products (shampoos, conditioners, body washes, lotions, cosmetics, etc.). Long-lasting perfume delivery is a key unmet consumer need within Beauty Care. Conventional products deliver good initial perfume performance, but the perfume fragrance benefit decays rapidly after product application. The desired outcome is to achieve long-lasting fragrance performance at 24 hours post-application with limited fragrance reduction. Fragrance intensity which does not diminish over a 24 hour time period and should remain "like just applied" at each of the following intervals: o Initial fragrance at delivery; o In-use fragrance -- working product into hair/skin; o In-use fragrance -- immediately after rinsing hair/skin; o At 4 hours (with damp hair/skin); o At 24 hours (with dry hair/skin); o At 24 hours with re-wetting of hair/skin. Fully developed or partially developed technologies/innovations for commercial development. We are not looking for conventional encapsulation/complexing such as complex coacervation, melamine, particulate complexes, etc. Nor are we interested in approaches that have shelf-stability issues via friction, sweat, sebum, etc.

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